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Regenerative therapies
to treat sensory disorders
and enhance healthy aging

Presbycusis and vision loss are among the most common age-related sensory declines, eroding independence and quality of life for millions. At SALUBRITAS, we are developing regenerative therapies to prevent and reverse these conditions by reawakening the body’s innate repair pathways and regenerating functional sensory cells. Our mission is to translate cutting-edge science into transformative therapeutics that restore sensory acuteness and enhance healthy aging.

Gene Therapies to treat genetic hearing loss in children

Congenital hearing loss affects millions of children worldwide and is a major cause of lifelong communication and developmental disability. Genetic mutations underlie over half of all cases, yet no disease-modifying therapies exist today. Recent breakthroughs in gene therapy and gene editing are opening a new era—one with the potential to restore hearing and fundamentally change the life trajectory of affected children.

Globally, about 500 million people live with disabling hearing loss, the majority of which is sensorineural in nature.

In children, SNHL affects approximately 1–2 per 1,000 live births, making it one of the most common congenital conditions. In adults, prevalence increases sharply with age, with over 50% of individuals older than 75 years experiencing clinically significant hearing loss. Noise exposure, ototoxic medications, and aging-related degeneration further contribute to the growing global burden.

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Understanding Sensorineural Hearing Loss and Inner-Ear Disorders

Sensorineural hearing loss (SNHL) and inner-ear disorders affect the sensory cells and neural pathways essential for hearing and balance. These conditions include age-related hearing loss (ARHL), noise-induced hearing loss (NIHL), drug-induced hearing loss (DIHL), as well as genetic forms of hearing loss that can appear at birth or develop over time. Associated disorders such as tinnitus, Ménière’s disease, and balance dysfunction further highlight the complex and widespread impact of inner-ear damage on daily life.

Science

Regenerative therapies to treat sensory disorders and enhance healthy aging

Gene Therapies to treat genetic hearing loss in children

Globally, about 500 million people live with disabling hearing loss, the majority of which is sensorineural in nature.

Understanding Sensorineural Hearing Loss and Inner-Ear Disorders

Regenerative therapies
to treat sensory disorders
and enhance healthy aging